Delivery Lot Splitting as an Enabler for Cross-docking and Fast Delivery

Integrated JIT Lot-Splitting Model with Setup Time Reduction for Different Delivery Policy using PSO Algorithm

This article develops an integrated JIT lot-splitting model for a single supplier and a single buyer. In this model we consider reduction of setup time, and the optimal lot size are obtained due to reduced setup time in the context of joint optimization for both buyer and supplier, under deterministic condition with a single product. Two cases are discussed: Single Delivery (SD) case, and Multi...

Internet of Things as Key Enabler for Sustainable Healthcare Delivery

Many errors occurring in healthcare are related to the lack of availability of important patient-related medical information. According to researchers, the use of information and communication technologies (ICTs) hold promise for increasing the accessibility of medical information and it is essential for patient safety. Furthermore, new developments in information and computing technologies wil...

Platform-as-a-Service as an Enabler for Global Software Development and Delivery

A Basic Period Approach for Solving the Economic Lot and Delivery Scheduling in Flexible Flow Lines

In this paper, the problem of lot sizing, scheduling and delivery of several items in a two-stage supply chain over a finite planning horizon is studied. Single supplier via a flexible flow line production system (FFL), produces several items and delivers them directly to an assembly facility. Based on basic period (BP) strategy, a new mixed zero-one nonlinear programming model has been develop...

A comprehensive study of HSA interaction with TMP using molecular docking and molecular dynamics methods: as an appropriate tool for drug delivery systems

Background: Human serum albumin (HSA) is one of the most prominent protein in human blood. Trimethoprim (TMP) is an efficient antibiotic drug for treatment of pneumocystis pneumonia (PCP). Patients with HIV/AIDS and cancer are extremely affected by the disease due to immune system deficiency. Objective: The aim of this study is to evaluate the molecular dynamics simulation (MD) of HSA with TMP...